Proximo-distal development in the legs of Drosophila.
نویسندگان
چکیده
The appendages of insects and vertebrates develop as extensions of the body wall. During development, a proximo-distal axis for growth and patterning is created in each appendage, in order to specify appendage length and allocation of pattern elements like joints and sensory organs. Here we use the expression of molecular markers to examine how PD development takes place in the legs of the fruit-fly Drosophila melanogaster. The data suggest a process of regionalization and progressive subdivision of an anlage similar to both insect embryonic segmentation and vertebrate somitogenesis.
منابع مشابه
jing is required for wing development and to establish the proximo-distal axis of the leg in Drosophila melanogaster.
The establishment of the proximo-distal (PD) axis in the legs of Drosophila melanogaster requires the expression of a nested set of transcription factors that are activated in discreet domains by secreted signaling molecules. The precise regulation of these transcription factor domains is critical for generating the stereotyped morphological characteristics that exist along the PD axis, such as...
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عنوان ژورنال:
- The International journal of developmental biology
دوره 42 3 شماره
صفحات -
تاریخ انتشار 1998